Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568960 | 0.83 | LMNA (0.46) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL14800383 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL9538691 | 0.80 | TRPA1 (0.44) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL108670 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL16954728 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL9539597 | 0.77 | ESR1 (0.44) | ALDH1A1HPGDMAPTTAS1R3TAS1R1 | |
| SCHEMBL6070107 | 0.77 | CES2 (0.54) | ALDH1A1LMNAHPGDCYP1A2CYP2C19 | |
| Ethylene SCHEMBL28813674 | 0.76 | LMNA (0.40) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL11080512 | 0.76 | MAPT (0.51) | ALDH1A1LMNAHPGDMAPTMEN1 | |
| SCHEMBL9442651 | 0.74 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002077-A1 | BENZIMIDAZOLES | FISONS PLC (GB) | 1993-02-04 | — | — | WO | disclosed |
| EP-0526033-A1 | Benzimidazoles | FISONS plc (GB) | 1993-02-03 | — | — | EP | disclosed |