Ethylene

Ethylene

SCHEMBL28813674

C=C.C=C.C=C.Cc1c(Cl)cccc1C(=S)S.N.N

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
ALDH1A1 P00352 6/20 0.39
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
MT-CO2 P00403 1/20 0.38
TTR P02766 1/20 0.38
PLA2G1B P04054 1/20 0.38
CYP1A2 P05177 1/20 0.38
PGR P06401 1/20 0.38
CYP3A4 P08684 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
AR P10275 1/20 0.38
CYP2C9 P11712 1/20 0.38
HTR2A P28223 1/20 0.38
CYP2C19 P33261 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9538669 0.76 ALDH1A1 (0.45) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL9568960 0.76 LMNA (0.46) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL14800383 0.75 ALDH1A1 (0.48) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL9568955 0.75 MAPT (0.49) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL8175043 0.74 TRPA1 (0.44) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL15633261 0.73 CES2 (0.52) LMNAALDH1A1HPGDCYP1A2CYP2C19
SCHEMBL9442651 0.72 ALDH1A1 (0.45) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL16954728 0.71 ALDH1A1 (0.48) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL29035888 0.71 P2RX7 (0.39) ALDH1A1MAPTHPGDHTTTAS1R3
SCHEMBL11080512 0.70 MAPT (0.51) LMNAALDH1A1MAPTHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103992265-A Double tribromo 1,3-bipyridine onium salt dimethylmethane, and preparation method, application method, recovery method and application thereof UNIV XI AN JIAOTONG 2014-08-20 CN disclosed