Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415841 | 0.79 | ALDH1A1 (0.58) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL31372050 | 0.79 | ALDH1A1 (0.58) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL1821100 | 0.78 | CES2 (0.59) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL28879951 | 0.77 | CES2 (0.52) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL31016401 | 0.77 | CES2 (0.52) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL1335840 | 0.77 | CES2 (0.52) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL15633261 | 0.77 | CES2 (0.52) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL20560729 | 0.77 | KAT6A (0.41) | CES2CES1ALDH1A1POLBMGLL | |
| SCHEMBL9538669 | 0.77 | ALDH1A1 (0.45) | ALDH1A1POLBLMNATSHRCYP1A2 | |
| SCHEMBL9148075 | 0.75 | CES2 (0.50) | CES2CES1ALDH1A1POLBMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126011-B2 | Reacting 2-chlorothiobenzoyl chloride with aromatic compound; drug for psychological disorder therapy; photopolymerization sensitizer | PROM LIMITED (GB) | 2006-10-24 | — | — | US | claimed |
| EP-1334096-B1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | PROM LTD (GB) | 2004-07-28 | — | — | EP | claimed |
| US-20030229233-A1 | Process for the preparation of thioxanthones | PROM LIMITED (GB) | 2003-12-11 | — | — | US | claimed |
| EP-1334096-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | Prom Limited (GB) | 2003-08-13 | — | — | EP | claimed |
| WO-2002040464-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | PROM LIMITED (GB) | 2002-05-23 | — | — | WO | claimed |
| CN-113861162-A | Preparation process of photoinitiator 2-/4-isopropyl thioxanthone | 喆鹿(山东)新材料有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-111138411-B | Ultraviolet light promoted synthesis method of thioxanthone compound | 浙江工业大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-107540580-B | Preparation method of acyl chloride and thioxanthone | 深圳有为技术控股集团有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-111138411-A | Ultraviolet light promoted synthesis method of thioxanthone compound | 浙江工业大学 | 2020-05-12 | — | — | CN | disclosed |
| US-9498473-B2 | Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance | Heptiva LLC (US) | 2016-11-22 | — | — | US | disclosed |
| US-9408841-B2 | Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance | Heptiva LLC (US) | 2016-08-09 | — | — | US | disclosed |
| CN-105241978-A | Method for determination of 2-isopropyl thioxanthone reaction intermediate content | Changzhou jiuri chemical co ltd | 2016-01-13 | — | — | CN | disclosed |
| EP-1334096-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | Prom Limited (GB) | 2003-08-13 | — | — | EP | disclosed |
| EP-1334096-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | Prom Limited (GB) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040464-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | PROM LIMITED (GB) | 2002-05-23 | — | — | WO | disclosed |
| WO-2002040464-A1 | FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES | PROM LIMITED (GB) | 2002-05-23 | — | — | WO | disclosed |
| EP-0026791-B1 | 2-ARYL-1,2-BENZISOTHIAZOLINONE-1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4369183-A | 2-Pyridyl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors | MERCK & CO., INC. (US) | 1983-01-18 | — | — | US | disclosed |
| US-4276298-A | 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors | MERCK & CO., INC. (US) | 1981-06-30 | — | — | US | disclosed |
| EP-0026791-A1 | 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1981-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229233-A1 | Process for the preparation of thioxanthones | TST, TPST2, SULT2A1 | CES2 92/4885CES1 169/4885ALDH1A1 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.