Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TACR3 | P29371 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539374 | 0.88 | TACR3 (0.45) | ITGB3ITGA2BENPP2TACR3TACR1 | |
| SCHEMBL7670973 | 0.85 | NPY5R (0.46) | ITGB3ITGA2BTACR3POLBNPY5R | |
| SCHEMBL9539144 | 0.80 | ENPP2 (0.45) | ENPP2NPY5RLPAR1LPAR3 | |
| SCHEMBL9539370 | 0.79 | ENPP2 (0.43) | ENPP2NPY5RLPAR1 | |
| SCHEMBL9699592 | 0.76 | TACR3 (0.40) | ITGB3ITGA2BTACR3TACR1NPY5R | |
| SCHEMBL9698397 | 0.75 | ITGB3 (0.39) | ITGB3ITGA2BTACR3TACR1NPY5R | |
| SCHEMBL7670805 | 0.75 | TACR1 (0.44) | SMN1; SMN2TACR3TACR1GPR88NPY5R | |
| SCHEMBL7665676 | 0.74 | TACR3 (0.43) | TACR3TACR1LMNANPY5R | |
| SCHEMBL5316226 | 0.73 | ITGB3 (0.46) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3658399 | 0.71 | ITGB3 (0.53) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |