Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540766 | 0.86 | SLC6A2 (0.44) | SLC6A9MAPTSLC6A2SLC6A4TSHR | |
| SCHEMBL9543443 | 0.82 | TSHR (0.43) | SLC6A9MAPTSLC6A2SLC6A4TSHR | |
| SCHEMBL10453097 | 0.82 | SLC6A9 (0.51) | SLC6A9MAPTSLC6A2SLC6A4HSD11B1 | |
| SCHEMBL9540784 | 0.81 | MEN1 (0.47) | SLC6A9MAPTSLC6A2SLC6A4HSD11B1 | |
| SCHEMBL9540773 | 0.80 | SLC6A2 (0.42) | SLC6A9MAPTSLC6A2SLC6A4TSHR | |
| SCHEMBL1355474 | 0.80 | HSD11B1 (0.52) | SLC6A9HSD11B1TSHRNPC1RAB9A | |
| SCHEMBL12917871 | 0.75 | ALDH1A1 (0.58) | SLC6A9MAPTHSD11B1TSHRHPGD | |
| SCHEMBL10453321 | 0.75 | MAPT (0.50) | SLC6A9MAPTSLC6A2SLC6A4TSHR | |
| SCHEMBL9542243 | 0.75 | POLB (0.46) | SLC6A9MAPTSLC6A2SLC6A4TSHR | |
| SCHEMBL9208637 | 0.75 | SLC6A9 (0.44) | SLC6A9MAPTSLC6A2SLC6A4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |