Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540822 | 0.83 | THRB (0.46) | SLC6A9TP53GAAMEN1KMT2A | |
| SCHEMBL9541768 | 0.80 | ALDH1A1 (0.42) | TP53MEN1KMT2AMAPTTSHR | |
| SCHEMBL9540839 | 0.78 | TP53 (0.41) | TP53GAAMEN1KMT2AMAPT | |
| SCHEMBL9541760 | 0.77 | TUBB4A (0.51) | SLC6A9MEN1KMT2AMAPTTHRB | |
| SCHEMBL9542171 | 0.75 | GAA (0.46) | SLC6A9TP53GAACYP1A2CYP3A4 | |
| SCHEMBL9199484 | 0.75 | TSHR (0.44) | SLC6A9TP53GAACYP1A2CYP3A4 | |
| SCHEMBL9584306 | 0.74 | SLC6A9 (0.44) | SLC6A9GAACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9542307 | 0.74 | MEN1 (0.42) | SLC6A9TP53GAACYP1A2CYP3A4 | |
| SCHEMBL10453097 | 0.74 | SLC6A9 (0.51) | SLC6A9GAAMEN1KMT2AMAPT | |
| SCHEMBL9544531 | 0.74 | KMT2A (0.37) | TP53MEN1KMT2ATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |