Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541768 | 0.92 | ALDH1A1 (0.42) | TP53ALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL9540822 | 0.88 | THRB (0.46) | TP53ALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL9584911 | 0.80 | MEN1 (0.39) | TP53ALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL9541760 | 0.79 | TUBB4A (0.51) | MEN1KMT2ATHRBMAPTPOLB | |
| SCHEMBL9199484 | 0.79 | TSHR (0.44) | TP53MEN1KMT2AMAPTTSHR | |
| SCHEMBL9544575 | 0.78 | SLC6A9 (0.39) | TP53ALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL9542205 | 0.78 | TSHR (0.43) | TP53MEN1KMT2AMAPTPOLB | |
| SCHEMBL9544531 | 0.77 | KMT2A (0.37) | TP53ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9542171 | 0.77 | GAA (0.46) | TP53MEN1KMT2ATHRBMAPT | |
| SCHEMBL9584306 | 0.76 | SLC6A9 (0.44) | ALDH1A1MEN1KMT2ATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |