Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912889 | 0.87 | MMP9 (0.52) | MMP2MMP9ATMTRPA1LMNA | |
| SCHEMBL893543 | 0.84 | ALDH1A1 (0.66) | ATMTRPA1LMNAALDH1A1HTT | |
| SCHEMBL893545 | 0.84 | ALDH1A1 (0.66) | ATMTRPA1LMNAALDH1A1HTT | |
| SCHEMBL4653160 | 0.82 | MMP2 (0.76) | MMP2MMP9ALDH1A1HTTGHSR | |
| SCHEMBL1750430 | 0.82 | MMP2 (0.76) | MMP2MMP9ALDH1A1HTTGHSR | |
| SCHEMBL6962263 | 0.80 | ALDH1A1 (0.72) | TRPA1LMNAALDH1A1HTTTSHR | |
| SCHEMBL15648472 | 0.80 | ALDH1A1 (0.72) | TRPA1LMNAALDH1A1HTTTSHR | |
| SCHEMBL8913925 | 0.80 | MMP9 (0.53) | MMP2MMP9LMNAALDH1A1HTT | |
| SCHEMBL23519421 | 0.79 | ALDH1A1 (0.65) | MMP2MMP9LMNAALDH1A1HTT | |
| SCHEMBL6997 | 0.79 | ALDH1A1 (0.65) | MMP2MMP9LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005014-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO-WEDROPHARM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |