Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 11/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9541138 | 0.80 | LMNA (0.38) | LMNATBXA2RENPP2TP53 | |
| SCHEMBL4988044 | 0.79 | LMNA (0.43) | LMNATBXA2RENPP2TP53MAPT | |
| SCHEMBL9635804 | 0.77 | LMNA (0.47) | LMNATBXA2RENPP2TP53MAPT | |
| SCHEMBL4984769 | 0.75 | SLC6A9 (0.48) | LMNAENPP2TP53KMT2A | |
| SCHEMBL9387295 | 0.73 | FAAH (0.45) | LMNAENPP2TP53MAPTMEN1 | |
| SCHEMBL9635952 | 0.72 | LMNA (0.45) | LMNATBXA2RENPP2TP53MAPT | |
| SCHEMBL4772386 | 0.72 | TP53 (0.51) | LMNATBXA2RENPP2TP53MAPT | |
| SCHEMBL17966877 | 0.70 | TP53 (0.62) | LMNATBXA2RENPP2TP53MAPT | |
| SCHEMBL6881772 | 0.70 | DRD4 (0.48) | LMNATP53MAPT | |
| SCHEMBL7833959 | 0.69 | LMNA (0.60) | LMNATBXA2RENPP2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014088-A1 | ANTIHISTAMINIC PIPERAZINYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-22 | — | — | WO | disclosed |