Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LCT | P09848 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962946 | 0.91 | HRH3 (0.36) | KDM1AFPR2HRH3PRMT5NR1H4 | |
| SCHEMBL8962940 | 0.91 | HRH3 (0.36) | KDM1AFPR2HRH3PRMT5NR1H4 | |
| SCHEMBL8962990 | 0.84 | KDM1A (0.44) | NAAAFAAHKDM1AFPR2HRH3 | |
| SCHEMBL8962982 | 0.84 | KDM1A (0.44) | NAAAFAAHKDM1AFPR2HRH3 | |
| SCHEMBL8962789 | 0.80 | NAAA (0.34) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8962781 | 0.80 | NAAA (0.34) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8963174 | 0.79 | FFAR4 (0.31) | NR1H4 | |
| SCHEMBL8963181 | 0.79 | FFAR4 (0.31) | NR1H4 | |
| SCHEMBL8962633 | 0.79 | HDAC2 (0.33) | NR1H4 | |
| SCHEMBL8962629 | 0.79 | HDAC2 (0.33) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |