SCHEMBL954314

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1008532	0.90	PTPN1 (0.48)	PTPN1SMN1; SMN2LMNAMAPTHPGD
	SCHEMBL3179234	0.85	NR4A2 (0.50)	PTPN1LMNAMAPTHPGDMAOB
	SCHEMBL1008504	0.84	SLC22A12 (0.57)	PTPN1LMNAMAOBSMPD1SLC22A12
	SCHEMBL235381	0.83	MAOB (0.48)	PTPN1SMN1; SMN2LMNAMAPTHPGD
	SCHEMBL237424	0.83	MAOB (0.48)	PTPN1SMN1; SMN2LMNAMAPTHPGD
	SCHEMBL7531827	0.82	PTPN1 (0.73)	PTPN1MAOBSMPD1NR4A2KMT2A
	SCHEMBL1633991	0.81	NR4A2 (0.65)	NR4A2NPC1RAB9AKMT2AMRGPRX4
	SCHEMBL31215373	0.81	NR4A2 (0.65)	NR4A2NPC1RAB9AKMT2AMRGPRX4
	SCHEMBL237290	0.81	MAOB (0.67)	SMN1; SMN2MAOBSLC22A12KMT2A
	SCHEMBL237393	0.81	HPGD (0.50)	PTPN1HPGDMAOBSLC22A12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.