SCHEMBL9544538

SCHEMBL9544538

CCC=C[SiH2]c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1493087 0.76 ALDH1A1 (0.32) MAOB
SCHEMBL28547612 0.73 LMNA (0.30)
SCHEMBL28151023 0.67 MEN1 (0.30)
SCHEMBL17862087 0.67 MAOB (0.48) MAOB
SCHEMBL8080827 0.67 MAOB (0.48) MAOB
SCHEMBL27957588 0.67 TRPA1 (0.39) TP53
Diethylamine SCHEMBL28794882 0.64 ALDH1A1 (0.34) TP53
SCHEMBL17862089 0.64 NFE2L2 (0.59) MAOB
SCHEMBL16309508 0.64 HPGD (0.44)
SCHEMBL23128456 0.64 KDM4E (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993017063-A1 CROSSLINKABLE CARBOSILANE POLYMER FORMULATIONS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-09-02 WO disclosed