Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453097 | 0.78 | SLC6A9 (0.51) | TRPM8NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9544541 | 0.77 | TRPM8 (0.46) | TRPM8NPC1RAB9ATSHRMEN1 | |
| SCHEMBL9208637 | 0.76 | SLC6A9 (0.44) | MEN1KMT2AGAASLC6A9ALDH1A1 | |
| SCHEMBL9542254 | 0.76 | TRPM8 (0.55) | TRPM8NPC1RAB9ATSHRMEN1 | |
| SCHEMBL9544546 | 0.76 | TRPM8 (0.55) | TRPM8NPC1RAB9ATSHRMEN1 | |
| SCHEMBL9540822 | 0.75 | THRB (0.46) | MEN1KMT2AGAASLC6A9ALDH1A1 | |
| SCHEMBL9540784 | 0.72 | MEN1 (0.47) | TRPM8RAB9AMEN1KMT2AGAA | |
| SCHEMBL12917871 | 0.72 | ALDH1A1 (0.58) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL10453321 | 0.71 | MAPT (0.50) | TRPM8TSHRMEN1KMT2ASLC6A9 | |
| SCHEMBL9542226 | 0.71 | TRPM8 (0.47) | TRPM8MEN1KMT2AGAASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |