Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549708 | 0.93 | TK1 (0.48) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL9549653 | 0.90 | TK1 (0.50) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL9549703 | 0.90 | TK1 (0.50) | TK1POLBALDH1A1LMNAALB | |
| Phosphoric Acid SCHEMBL3095605 | 0.87 | TK1 (0.52) | TK1DHFR | |
| SCHEMBL19242604 | 0.86 | TK1 (0.53) | TK1POLBALDH1A1LMNAALB | |
| SCHEMBL78118 | 0.86 | TK1 (0.53) | TK1POLBALDH1A1LMNAALB | |
| Pyrophosphoric Acid SCHEMBL1269545 | 0.85 | POLB (0.54) | TK1POLBDHFR | |
| Triphosphate SCHEMBL81707 | 0.83 | POLB (0.55) | TK1POLBDHFR | |
| SCHEMBL3154831 | 0.82 | POLB (0.57) | TK1POLBDHFR | |
| SCHEMBL9549776 | 0.81 | TK1 (0.53) | TK1POLBLMNAALBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218088-A | Process for preparing dithiophosphate oligonucleotide analogs via nucleoside thiophosphoramidite intermediates | PURDUE RESEARCH FOUNDATION (US) | 1993-06-08 | — | — | US | disclosed |