Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94957 | 0.81 | GLA (0.37) | TRPV1RAB9ANPC1KMT2APDK1 | |
| SCHEMBL94995 | 0.72 | HSD17B2 (0.41) | TRPV1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL95242 | 0.70 | PHGDH (0.56) | RAB9ANPC1KMT2APDK1PDK2 | |
| SCHEMBL5188223 | 0.69 | KMT2A (0.53) | RAB9ANPC1KMT2APDK1PDK2 | |
| SCHEMBL5706504 | 0.66 | CETP (0.71) | RAB9AKMT2APDK1PDK2PDK3 | |
| SCHEMBL12666574 | 0.66 | POLB (0.49) | TRPV1RAB9ANPC1KMT2APDK1 | |
| SCHEMBL11136765 | 0.66 | POLB (0.49) | TRPV1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL95284 | 0.66 | PDK1 (0.68) | RAB9ANPC1KMT2APDK1PDK2 | |
| SCHEMBL10989896 | 0.66 | MAPT (0.61) | RAB9ANPC1KMT2APDK1PDK2 | |
| SCHEMBL9767724 | 0.66 | KMT2A (0.79) | TRPV1RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058085-A1 | Deuterium Modified Benzimidazoles | CONCERT PHARMACEUTICALS, INC. | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058085-A1 | Deuterium Modified Benzimidazoles | POLRMT, EIF2AK2, DUT | TRPV1 3554/4885RAB9A 3625/4885NPC1 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.