Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557984 | 0.87 | L3MBTL1 (0.41) | HSD11B1APAF1UBE2NKMT2AALDH1A1 | |
| SCHEMBL9825031 | 0.82 | KMT2A (0.42) | HSD11B1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL10779169 | 0.75 | TSHR (0.35) | SMN1; SMN2PDK1PDK2PDK3PDK4 | |
| SCHEMBL9557559 | 0.69 | CYP3A4 (0.49) | KMT2AMEN1MAPTLMNACYP1A2 | |
| SCHEMBL9557948 | 0.64 | HSD11B1 (0.49) | HSD11B1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL2458633 | 0.64 | HTR6 (0.58) | HSD11B1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9557416 | 0.64 | TSHR (0.46) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9825414 | 0.63 | CYP2C9 (0.48) | KMT2AMEN1MAPTLMNACYP1A2 | |
| SCHEMBL9557233 | 0.63 | TSHR (0.41) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL1000532 | 0.63 | MAPT (0.60) | KMT2AALDH1A1MAPTLMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |