Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557839 | 0.87 | HSD11B1 (0.40) | L3MBTL1HSD11B1APAF1UBE2NKMT2A | |
| SCHEMBL9825031 | 0.80 | KMT2A (0.42) | HSD11B1KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10775720 | 0.77 | TSHR (0.40) | KMT2ATSHRLMNA | |
| SCHEMBL9557233 | 0.74 | TSHR (0.41) | KMT2ATSHRALDH1A1MEN1LMNA | |
| SCHEMBL9557487 | 0.71 | TSHR (0.47) | HSD11B1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9557674 | 0.67 | ALDH1A1 (0.49) | L3MBTL1HSD11B1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9557515 | 0.67 | TSHR (0.52) | KMT2ATSHRSMN1; SMN2LMNA | |
| SCHEMBL9557703 | 0.65 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1PPARGPOLB | |
| SCHEMBL9558054 | 0.65 | ALDH1A1 (0.46) | L3MBTL1KMT2AALDH1A1MAPT | |
| SCHEMBL27317243 | 0.65 | TSHR (0.56) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |