SCHEMBL9560352

SCHEMBL9560352

Cc1ccc(C(Cl)(COCc2cccc(Oc3ccccc3)c2)C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.42
CETP P11597 5/20 0.39
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.38
ADRA2A P08913 1/20 0.38
CNR1 P21554 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
FFAR4 Q5NUL3 2/20 0.36
MMP13 P45452 1/20 0.36
FAAH O00519 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TACR1 P25103 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560366 0.90 KDM4E (0.48) FFAR1CETPTDP1LMNAADRA2A
SCHEMBL9560419 0.89 KDM4E (0.39) FFAR1CETPTDP1LMNAADRA2A
SCHEMBL9560713 0.88 LTA4H (0.46) FFAR1CETPTDP1LMNAATM
SCHEMBL9560464 0.87 MAPK14 (0.47) FFAR1CETPFFAR4TACR1
SCHEMBL9560435 0.84 FFAR1 (0.45) FFAR1CETPTDP1LMNAADRA2A
SCHEMBL9561530 0.83 CETP (0.39) FFAR1CETPTDP1LMNAADRA2A
SCHEMBL9561537 0.83 CETP (0.39) FFAR1CETPTDP1LMNAADRA2A
SCHEMBL9558585 0.83 FFAR1 (0.47) FFAR1CETPTDP1LMNAADRA2A
SCHEMBL9560778 0.81 ALDH1A1 (0.39) FFAR1CETPLMNAFFAR4KDM4E
SCHEMBL9560848 0.81 ALDH1A1 (0.42) FFAR1CETPLMNAATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225607-A Multistage etherification or dehydrohalogenation and reductive dechlorination IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-07-06 US disclosed
US-5196610-A INSECTICIDAL ETHERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-03-23 US disclosed
EP-0211561-B1 INSECTICIDAL ETHERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-03-11 EP disclosed
EP-0211561-A1 Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-02-25 EP disclosed