Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560419 | 0.90 | KDM4E (0.39) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9560352 | 0.90 | FFAR1 (0.42) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9560713 | 0.89 | LTA4H (0.46) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9560464 | 0.89 | MAPK14 (0.47) | CETPLTA4HMAOBFFAR1FFAR4 | |
| SCHEMBL9560778 | 0.85 | ALDH1A1 (0.39) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9560804 | 0.85 | TTR (0.39) | KDM4EALDH1A1HTTSMN1; SMN2LTA4H | |
| SCHEMBL9560466 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9339448 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9560848 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2CETPLTA4H | |
| SCHEMBL9560424 | 0.82 | MAPK14 (0.40) | ALDH1A1CETPMAOBFFAR4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |