Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560419 | 0.93 | KDM4E (0.39) | ALDH1A1LMNAHTTSMN1; SMN2CETP | |
| SCHEMBL9560848 | 0.88 | ALDH1A1 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9560424 | 0.87 | MAPK14 (0.40) | ALDH1A1LMNAPPARGPPARACETP | |
| SCHEMBL9560407 | 0.87 | LMNA (0.40) | ALDH1A1LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL27281063 | 0.85 | ALDH1A1 (0.39) | ALDH1A1LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9560366 | 0.85 | KDM4E (0.48) | ALDH1A1LMNAHTTSMN1; SMN2CETP | |
| SCHEMBL27277060 | 0.82 | LMNA (0.40) | ALDH1A1LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9561663 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9561658 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9560352 | 0.81 | FFAR1 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |