Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.61 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563324 | 0.89 | BCHE (0.69) | BCHEPARP14LTA4HPTGS2 | |
| SCHEMBL9563267 | 0.82 | BCHE (0.53) | BCHEPARP14HPGDSNPC1MLNR | |
| SCHEMBL9563224 | 0.81 | LTA4H (0.57) | LTA4HPTGS2CHRNB4CHRNA3LMNA | |
| SCHEMBL9563333 | 0.81 | CYP2D6 (0.60) | BCHEPARP14HPGDSNPC1RAB9A | |
| SCHEMBL18788213 | 0.79 | LTA4H (0.73) | LTA4HPTGS2CHRNB4CHRNA3 | |
| SCHEMBL9563354 | 0.78 | BCHE (0.54) | BCHEPARP14HPGDSNPC1MLNR | |
| SCHEMBL13202242 | 0.78 | LTA4H (0.72) | LTA4HPTGS2CHRNB4CHRNA3 | |
| SCHEMBL9563182 | 0.78 | DRD2 (0.53) | BCHEPARP14NPC1MLNRNR1I2 | |
| SCHEMBL9563236 | 0.78 | BCHE (0.55) | BCHEPARP14ACHESLC6A3FAAH | |
| SCHEMBL9563348 | 0.78 | ALDH1A1 (0.61) | BCHEPARP14NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |