Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564440 | 1.00 | L3MBTL1 (0.37) | L3MBTL1CYP1A2SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9564345 | 0.70 | KDR (0.34) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL9564349 | 0.70 | KDR (0.34) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL9564365 | 0.69 | KMT2A (0.43) | L3MBTL1CYP1A2SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9564372 | 0.69 | KMT2A (0.43) | L3MBTL1CYP1A2SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9564366 | 0.68 | GAA (0.50) | CYP1A2SMN1; SMN2ALDH1A1MAPK1POLB | |
| SCHEMBL9564371 | 0.68 | GAA (0.50) | CYP1A2SMN1; SMN2ALDH1A1MAPK1POLB | |
| SCHEMBL9564356 | 0.68 | KDM4E (0.42) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL27898719 | 0.67 | SMN1; SMN2 (0.47) | CYP1A2SMN1; SMN2ALDH1A1MAPK1POLB | |
| SCHEMBL9564389 | 0.66 | MAPT (0.49) | SMN1; SMN2ALDH1A1MAPK1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |