Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | GPR39 | O43194 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422419 | 0.78 | HIF1A (0.49) | KDM4EMAPK1HIF1AATMMLLT1 | |
| SCHEMBL9564368 | 0.76 | HIF1A (0.44) | KDM4EMAPK1HIF1AATMMLLT1 | |
| SCHEMBL9564402 | 0.71 | VCP (0.49) | KDM4EHIF1AATMMLLT1RAB9A | |
| SCHEMBL9564361 | 0.69 | RAB9A (0.49) | HIF1ANPC1RAB9AVCPMEN1 | |
| SCHEMBL9564375 | 0.69 | HIF1A (0.43) | KDM4EMAPK1HIF1AATMMLLT1 | |
| SCHEMBL4945126 | 0.68 | NOTUM (0.40) | NPC1RAB9A | |
| SCHEMBL1544246 | 0.66 | NOTUM (0.62) | KDM4EMAPK1RAB9AKMT2A | |
| SCHEMBL13096156 | 0.65 | HIF1A (0.50) | KDM4EMAPK1HIF1AATMMLLT1 | |
| SCHEMBL9564425 | 0.65 | KDM4E (0.44) | KDM4EMAPK1HIF1AATMHRH4 | |
| SCHEMBL1544363 | 0.65 | HSP90AA1 (0.37) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |