Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422419 | 0.68 | HIF1A (0.49) | KDM4EATMMAPK1VCPRECQL | |
| SCHEMBL8542219 | 0.67 | CRHR1 (0.51) | KDM4EATMMAPK1CHRM4VCP | |
| SCHEMBL9564361 | 0.67 | RAB9A (0.49) | VCPMEN1KMT2AHIF1A | |
| SCHEMBL9564368 | 0.66 | HIF1A (0.44) | KDM4EATMMAPK1VCPHRH4 | |
| SCHEMBL9564390 | 0.65 | KDM4E (0.41) | KDM4EATMMAPK1VCPMEN1 | |
| SCHEMBL9564375 | 0.62 | HIF1A (0.43) | KDM4EATMMAPK1CRHR1HIF1A | |
| SCHEMBL17700718 | 0.61 | CRHR1 (0.51) | KDM4EMAPK1MEN1KMT2ACRHR1 | |
| SCHEMBL9653485 | 0.61 | MEN1 (0.55) | KDM4ECHRM4MEN1KMT2ACRHR1 | |
| SCHEMBL13096156 | 0.61 | HIF1A (0.50) | KDM4EATMMAPK1KMT2ABRD4 | |
| SCHEMBL9564359 | 0.61 | HCN1 (0.39) | KDM4EATMMAPK1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |