Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564387 | 1.00 | TP53 (0.35) | TP53ALDH1A1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL9564369 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9564376 | 0.73 | GAA (0.48) | TP53ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9564370 | 0.73 | GAA (0.48) | TP53ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9564386 | 0.71 | DAO (0.41) | ALDH1A1SMN1; SMN2RAB9AL3MBTL1DAO | |
| SCHEMBL9564365 | 0.70 | KMT2A (0.43) | TP53ALDH1A1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL9564372 | 0.70 | KMT2A (0.43) | TP53ALDH1A1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL9564382 | 0.69 | KMT2A (0.44) | ALDH1A1SMN1; SMN2RAB9ADAO | |
| SCHEMBL27830231 | 0.68 | TP53 (0.47) | TP53ALDH1A1SMN1; SMN2RAB9ADAO | |
| SCHEMBL9564422 | 0.68 | CES2 (0.40) | RAB9ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |