Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564599 | 1.00 | LMNA (0.48) | LMNAADRB1SIGMAR1HTR7CNR2 | |
| SCHEMBL9564604 | 0.84 | RXFP1 (0.49) | LMNAADRB1SIGMAR1 | |
| SCHEMBL9564601 | 0.84 | RXFP1 (0.49) | LMNAADRB1SIGMAR1 | |
| SCHEMBL11492529 | 0.82 | HTR6 (0.43) | LMNASIGMAR1HTR7CHRNB2CHRNB4 | |
| SCHEMBL11493511 | 0.82 | HTR6 (0.43) | LMNASIGMAR1HTR7CHRNB2CHRNB4 | |
| SCHEMBL13539860 | 0.80 | CHRNB2 (0.49) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11492527 | 0.75 | SIGMAR1 (0.41) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11489490 | 0.72 | LTA4H (0.48) | SLC6A2SLC6A4 | |
| SCHEMBL4356995 | 0.70 | CHRNB2 (0.70) | LMNAADRB1SIGMAR1SLC6A4CHRNB2 | |
| SCHEMBL11493943 | 0.70 | CYP1A2 (0.38) | LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551617-A2 | Cinnamyl piperazine derivatives method of manufacturing the same and agricultural/horticultural fungicides containing cinnamyl piperazine derivatives | UBE INDUSTRIES, LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |