Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856901 | 0.93 | MAPT (0.40) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL2852552 | 0.89 | MEN1 (0.51) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL2850694 | 0.88 | MAPT (0.41) | MEN1KMT2ALMNAMAPTP2RX7 | |
| SCHEMBL2850809 | 0.88 | MAPT (0.43) | KMT2ALMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL2853465 | 0.87 | RAB9A (0.44) | LMNAMAPTGPR6ACHENPSR1 | |
| SCHEMBL2857582 | 0.87 | MAPT (0.42) | MEN1KMT2APKMPDK1PDK2 | |
| SCHEMBL2858182 | 0.87 | P2RX7 (0.44) | LMNAMAPTP2RX7NPSR1CYP1A2 | |
| SCHEMBL2860522 | 0.87 | MAPT (0.48) | MEN1KMT2AMAPTNPSR1CYP1A2 | |
| SCHEMBL2853182 | 0.86 | MAPT (0.42) | LMNAPDK2MAPTP2RX7GPR6 | |
| SCHEMBL2852244 | 0.85 | MAPT (0.48) | MEN1KMT2AMAPTGPR6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |