Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690668 | 0.87 | ADRA1D (0.46) | USP2POLBTSHRADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9564793 | 0.86 | ADRA1D (0.41) | USP2POLBTSHRADRA1DADRA1A | |
| Oxalic Acid SCHEMBL9876420 | 0.85 | ADRA1D (0.44) | USP2POLBTSHRADRA1DADRA1A | |
| Oxalic Acid SCHEMBL9876418 | 0.85 | ADRA1D (0.44) | USP2POLBTSHRADRA1DADRA1A | |
| Fumaric Acid SCHEMBL9630586 | 0.81 | ADRA1D (0.41) | USP2POLBTSHRADRA1DADRA1A | |
| SCHEMBL9564808 | 0.79 | HTR2A (0.38) | USP2ADRA1DADRA1AHTR1ASIGMAR1 | |
| SCHEMBL9564990 | 0.78 | NR4A2 (0.40) | USP2TSHR | |
| SCHEMBL9564774 | 0.75 | ALDH1A1 (0.44) | TSHR | |
| SCHEMBL9538250 | 0.71 | ADRA1D (0.47) | USP2POLBTSHRADRA1DADRA1A | |
| SCHEMBL9565024 | 0.70 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |