Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18795683 | 0.81 | L3MBTL1 (0.64) | L3MBTL1PKMKMT2AMEN1TDP1 | |
| SCHEMBL3717527 | 0.80 | KMT2A (0.72) | L3MBTL1PKMKMT2AMEN1TDP1 | |
| SCHEMBL28987574 | 0.75 | HSD17B10 (0.54) | L3MBTL1KMT2ATDP1TSHRRAB9A | |
| SCHEMBL9661173 | 0.75 | PKM (0.68) | L3MBTL1PKMKMT2AMEN1TDP1 | |
| SCHEMBL2467263 | 0.73 | TDP1 (0.55) | L3MBTL1PKMKMT2AMEN1TDP1 | |
| SCHEMBL29412876 | 0.73 | NAPRT (0.61) | L3MBTL1PKMTDP1TSHRMAP2K1 | |
| SCHEMBL1807364 | 0.73 | NAPRT (0.61) | L3MBTL1PKMKMT2AMEN1TDP1 | |
| SCHEMBL167456 | 0.73 | NAPRT (0.61) | L3MBTL1PKMTDP1TSHRMAP2K1 | |
| SCHEMBL9565846 | 0.72 | TUBB4A (0.52) | RAB9ASMN1; SMN2NPC1KDM4ECASP3 | |
| SCHEMBL812065 | 0.72 | KDM4E (0.59) | L3MBTL1PKMKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526732-A2 | Processes for the preparation of heterocyclic thiocarbamates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-10 | — | — | EP | disclosed |