SCHEMBL9566152

SCHEMBL9566152

CON(C)C(C)=NN=C(c1ccc(F)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.36
CXCR2 P25025 2/20 0.34
RAB9A P51151 2/20 0.33
TAS2R14 Q9NYV8 1/20 0.33
CXCR1 P25024 1/20 0.33
MLYCD O95822 1/20 0.32
HSD11B1 P28845 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.31
P2RX3 P56373 1/20 0.31
HTR1A P08908 1/20 0.31
HTR1D P28221 1/20 0.31
HTR1B P28222 1/20 0.31
STS P08842 1/20 0.31
ALDH1A1 P00352 1/20 0.31
FFAR1 O14842 1/20 0.30
MAOB P27338 1/20 0.30
YAP1 P46937 1/20 0.30
TEAD4 Q15561 1/20 0.30
TEAD2 Q15562 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9566100 0.90 ALDH1A1 (0.35) CXCR2RAB9ACXCR1KMT2AALDH1A1
SCHEMBL9566058 0.80 CXCR2 (0.37) CXCR2RAB9ATAS2R14CXCR1MLYCD
SCHEMBL9565958 0.79 DRD2 (0.35) CXCR2CXCR1KMT2AHTR1AHTR1D
SCHEMBL9565985 0.78 CYP11B1 (0.34) CXCR2RAB9ACXCR1KMT2AALDH1A1
SCHEMBL9566056 0.77 CYP11B1 (0.34) CXCR2RAB9ACXCR1KMT2AMEN1
SCHEMBL9566079 0.76 NFE2L2 (0.38) RAB9AKMT2AMEN1ALDH1A1MAOB
SCHEMBL9566039 0.76 ENPP1 (0.35) CXCR2RAB9AALDH1A1
SCHEMBL9566161 0.76 PSEN1 (0.35) CXCR2KMT2AMEN1HTR1AHTR1D
SCHEMBL21358357 0.74 MLYCD (0.56) CXCR2RAB9ACXCR1MLYCDHSD11B1
SCHEMBL8538819 0.74 CXCR2 (0.41) CXCR2TAS2R14CXCR1HSD11B1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566534-A1 Derivatives of benzophenone CIBA-GEIGY AG (CH) 1993-10-20 EP claimed
EP-0566534-A1 Derivatives of benzophenone CIBA-GEIGY AG (CH) 1993-10-20 EP disclosed