Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516385 | 0.84 | OPRL1 (0.50) | OPRL1TSHRCYP3A4CYP2D6MEN1 | |
| SCHEMBL9566388 | 0.81 | CXCR4 (0.53) | OPRL1TSHRCYP3A4CYP2D6HSD17B10 | |
| SCHEMBL16984334 | 0.80 | ACHE (0.51) | OPRL1TSHRCYP3A4CYP2D6MEN1 | |
| SCHEMBL6331329 | 0.78 | ALDH1A1 (0.49) | OPRL1TSHRCYP3A4CYP2D6MEN1 | |
| SCHEMBL9566488 | 0.78 | CYP2D6 (0.48) | TSHRCYP3A4CYP2D6MEN1CYP2C9 | |
| SCHEMBL31516365 | 0.78 | CYP3A4 (0.49) | OPRL1TSHRCYP3A4CYP2D6MEN1 | |
| SCHEMBL19325429 | 0.76 | DOCK5 (0.46) | OPRL1TSHRCYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL17608949 | 0.75 | TSHR (0.52) | OPRL1TSHRCYP3A4CYP2D6MEN1 | |
| SCHEMBL31516337 | 0.75 | SIGMAR1 (0.49) | OPRL1CYP2D6SIGMAR1 | |
| SCHEMBL31516388 | 0.74 | LMNA (0.57) | OPRL1ALDH1A1CYP2C19KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | claimed |
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |