Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566402 | 0.81 | OPRL1 (0.48) | SCN9ACYP3A4CYP2D6TSHRHSD17B10 | |
| SCHEMBL16984334 | 0.76 | ACHE (0.51) | CYP3A4CYP2D6TSHRACHEHSD17B10 | |
| SCHEMBL9566488 | 0.73 | CYP2D6 (0.48) | SCN9ACYP3A4CYP2D6TSHR | |
| SCHEMBL1709213 | 0.70 | SCN9A (0.58) | SCN9ACYP3A4ACHEBACE1HSD17B10 | |
| SCHEMBL8707233 | 0.70 | CXCR4 (1.00) | CXCR4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17712839 | 0.70 | SIGMAR1 (0.48) | CYP3A4CYP2D6TSHRACHEHSD17B10 | |
| SCHEMBL9566484 | 0.69 | LMNA (0.43) | CYP3A4CYP2D6TSHR | |
| SCHEMBL19325429 | 0.69 | DOCK5 (0.46) | CYP3A4CYP2D6TSHRHSD17B10OPRL1 | |
| SCHEMBL8881882 | 0.69 | POLB (0.49) | CXCR4CYP3A4HSD17B10OPRL1 | |
| SCHEMBL10071962 | 0.69 | SCN9A (0.57) | SCN9ACYP3A4ACHEBACE1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |