Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19356065 | 0.81 | PDGFRB (0.53) | PDGFRBPDGFRAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9566448 | 0.80 | KDM4E (0.58) | ALDH1A1NPC1RAB9AHTTKMT2A | |
| SCHEMBL9566530 | 0.78 | DHFR (0.60) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL11002112 | 0.77 | NCOA1 (0.71) | — | |
| SCHEMBL31084656 | 0.77 | MAPT (0.72) | PDGFRBPDGFRAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3134094 | 0.77 | MAPT (0.72) | PDGFRBPDGFRAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8489079 | 0.76 | KDM4E (0.58) | MAPTALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL30955240 | 0.75 | ALDH1A1 (0.67) | PDGFRBPDGFRAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14851821 | 0.75 | TUBB4A (0.51) | PDGFRBPDGFRAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28075509 | 0.75 | GRK6 (0.60) | PDGFRBPDGFRAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |