Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566730 | 0.94 | KDM4E (0.45) | LMNAGAANPC1RAB9ATAAR1 | |
| SCHEMBL9566906 | 0.88 | SPHK2 (0.45) | LMNASMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL9566834 | 0.86 | LOXL2 (0.41) | CYP1A2CYP2C9CYP2C19LOXLOXL2 | |
| SCHEMBL9566858 | 0.84 | HPGD (0.43) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL9566810 | 0.81 | LOXL2 (0.41) | SMN1; SMN2CYP1A2CYP2C9CYP2C19LOX | |
| SCHEMBL9517034 | 0.80 | LNPEP (0.44) | MAPTL3MBTL1LNPEPKDM4EMEN1 | |
| SCHEMBL9566818 | 0.79 | ALDH1A1 (0.44) | GAAL3MBTL1LNPEPKDM4EMEN1 | |
| SCHEMBL9354128 | 0.76 | LOXL2 (0.48) | MAPK1CYP1A2CYP2C9CYP2C19LOX | |
| SCHEMBL9706102 | 0.76 | LOXL2 (0.46) | GAANPC1RAB9ATAAR1MAPK1 | |
| SCHEMBL9566886 | 0.75 | MEN1 (0.41) | LMNASMN1; SMN2MAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |