Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485990 | 0.80 | CCR5 (0.42) | ALOX15APPALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29437378 | 0.79 | ALOX15 (0.46) | ALOX15ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL1874361 | 0.79 | ALOX15 (0.46) | ALOX15ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL8644984 | 0.78 | CRHR1 (0.46) | ALOX15APPALDH1A1TSHRHSD17B10 | |
| SCHEMBL15281583 | 0.78 | MAPT (0.42) | APPALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL14808309 | 0.78 | HRH4 (0.41) | APPALDH1A1MAPK1MAPTPYCR1 | |
| SCHEMBL454679 | 0.76 | ALDH1A1 (0.40) | APPALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL6726449 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10MAPK1TDP1 | |
| SCHEMBL1932115 | 0.76 | ALDH1A1 (0.41) | ALOX15ALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL13830595 | 0.76 | MAPK1 (0.38) | APPALDH1A1TSHRHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558857-A1 | Method for the manufacture of P-bromodimethyl aniline | IMI (TAMI) INSTITUTE FOR RESEARCH & DEVELOPMENT LTD. (IL) | 1993-09-08 | — | — | EP | disclosed |