Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | YAP1 | P46937 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568095 | 0.87 | TGM2 (0.48) | POLBSMN1; SMN2ALDH1A1LMNAITGB3 | |
| SCHEMBL9568163 | 0.81 | ACHE (0.44) | MEN1KMT2APOLBSMN1; SMN2ACHE | |
| SCHEMBL8407202 | 0.79 | YAP1 (0.49) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7300740 | 0.79 | MAPT (0.52) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9568156 | 0.78 | TGM2 (0.43) | POLBSMN1; SMN2ALDH1A1LMNAITGB3 | |
| SCHEMBL9176347 | 0.78 | MAPT (0.43) | SMN1; SMN2ALDH1A1LMNAITGB3ITGA2B | |
| SCHEMBL9568191 | 0.76 | YAP1 (0.43) | KMT2APOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9568146 | 0.75 | YAP1 (0.43) | KMT2APOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9568145 | 0.74 | EPHX1 (0.47) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL8407952 | 0.74 | ITGB3 (0.49) | POLBSMN1; SMN2ALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |