Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320513 | 0.88 | LMNA (0.59) | LMNATHRBKMT2AMEN1KCNH2 | |
| SCHEMBL9321206 | 0.87 | THRB (0.64) | LMNATHRBKMT2AMEN1KCNH2 | |
| SCHEMBL9321227 | 0.83 | POLB (0.49) | LMNATHRBKMT2ASMN1; SMN2NLRP3 | |
| SCHEMBL9320372 | 0.83 | LMNA (0.53) | LMNATHRBKMT2AMEN1KCNH2 | |
| SCHEMBL9514633 | 0.83 | LMNA (0.80) | LMNATHRBKMT2AMEN1KCNH2 | |
| Hydrochloric Acid SCHEMBL9513006 | 0.82 | LMNA (0.78) | LMNATHRBKMT2AMEN1KCNH2 | |
| SCHEMBL9568289 | 0.81 | CACNA1G (0.57) | THRBKMT2AMEN1FAAHKDM4E | |
| SCHEMBL9513169 | 0.80 | LMNA (0.65) | LMNATHRBKMT2AMEN1KCNH2 | |
| SCHEMBL9568292 | 0.80 | SIGMAR1 (0.56) | THRBKMT2AMEN1KDM4EPOLB | |
| SCHEMBL9321264 | 0.80 | LMNA (0.54) | LMNATHRBKMT2AMEN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524146-A1 | Aminosubstituted Piperazinederivatives | CIBA-GEIGY AG (CH) | 1993-01-20 | — | — | EP | disclosed |