SCHEMBL9568620

SCHEMBL9568620

C=CC(=O)Oc1cccc(S(=O)(=O)NCC(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 1/20 0.46
ALDH1A1 P00352 6/20 0.42
GAA P10253 3/20 0.42
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
PDK1 Q15118 2/20 0.42
PDK2 Q15119 2/20 0.42
PDK3 Q15120 2/20 0.42
PDK4 Q16654 2/20 0.42
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 2/20 0.40
PKM P14618 1/20 0.40
LMNA P02545 3/20 0.39
POLB P06746 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568500 0.86 MEP1B (0.49) MEP1BALDH1A1GAAL3MBTL1KMT2A
SCHEMBL9568615 0.84 ALDH1A1 (0.52) ALDH1A1GAAHPGDPDK1PDK2
SCHEMBL3251700 0.84 MEP1B (0.45) MEP1BALDH1A1GAAHPGDL3MBTL1
SCHEMBL9568752 0.83 HTR2B (0.44) MEP1BALDH1A1GAAL3MBTL1LMNA
SCHEMBL9568612 0.81 SMN1; SMN2 (0.42) MEP1BALDH1A1KMT2ALMNAPOLB
SCHEMBL9568524 0.81 ALDH1A1 (0.52) MEP1BALDH1A1KMT2ALMNAMEN1
SCHEMBL9568654 0.81 L3MBTL1 (0.47) MEP1BALDH1A1L3MBTL1TDP1LMNA
SCHEMBL27403596 0.79 MEP1B (0.41) MEP1BL3MBTL1
SCHEMBL9568692 0.78 LMNA (0.54) MEP1BALDH1A1HPGDL3MBTL1KMT2A
SCHEMBL9568821 0.78 PGR (0.53) ALDH1A1KMT2APKMPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed