SCHEMBL9568692

SCHEMBL9568692

C=CC(=O)Oc1cccc(S(=O)(=O)NC(C)(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
NPC1 O15118 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
RAB9A P51151 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
PARG Q86W56 1/20 0.43
MEP1B Q16820 1/20 0.40
BRD4 O60885 1/20 0.40
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
JAK2 O60674 3/20 0.39
DUT P33316 2/20 0.38
FFAR4 Q5NUL3 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568654 0.85 L3MBTL1 (0.47) LMNAMAPTSMN1; SMN2MEP1BALDH1A1
SCHEMBL9568695 0.83 CA12 (0.47) LMNAMAPTHPGDSMN1; SMN2ALDH1A1
SCHEMBL3242511 0.83 LMNA (0.52) LMNAKDM4EMEN1NPC1MAPT
SCHEMBL27403596 0.82 MEP1B (0.41) MEP1BFFAR4KEAP1NFE2L2KAT6A
SCHEMBL9568500 0.81 MEP1B (0.49) LMNAMAPTKMT2AMEP1BBRD4
SCHEMBL9568752 0.81 HTR2B (0.44) LMNAMEP1BALDH1A1KAT6AL3MBTL1
SCHEMBL8784007 0.80 THRB (0.41) LMNAMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL9568524 0.80 ALDH1A1 (0.52) LMNAMEN1KMT2AMEP1BALDH1A1
SCHEMBL9579704 0.79 LMNA (0.40) LMNAMEN1MAPTHPGDKMT2A
SCHEMBL27403580 0.79 RORA (0.38) LMNAMEP1BALDH1A1POLBFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed