SCHEMBL9568699

SCHEMBL9568699

C=CC(=O)Oc1cccc(NS(=O)(=O)CC)c1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.43
MAP2K1 Q02750 3/20 0.42
HPGD P15428 5/20 0.42
THRB P10828 3/20 0.42
BRD4 O60885 2/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
THRA P10827 1/20 0.39
AURKA O14965 1/20 0.39
KDR P35968 1/20 0.39
AURKB Q96GD4 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA1A P35348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568700 0.86 POLB (0.52) EGFRMAP2K1HPGDALDH1A1SMN1; SMN2
SCHEMBL9568488 0.82 HPGD (0.54) HPGDTHRBLMNASMN1; SMN2
SCHEMBL3249530 0.82 HPGD (0.43) MAP2K1HPGDBRD4LMNAALDH1A1
SCHEMBL9568805 0.80 LMNA (0.52) HPGDTHRBLMNAALDH1A1PKM
SCHEMBL9568712 0.79 TCF4 (0.58) HPGDLMNAALDH1A1PKMSMN1; SMN2
SCHEMBL9770316 0.78 EGFR (0.47) EGFRTHRBALDH1A1PKMSMN1; SMN2
SCHEMBL17227610 0.77 LMNA (0.61) HPGDLMNAALDH1A1PKMSMN1; SMN2
SCHEMBL9568667 0.77 TGM2 (0.55) EGFRHPGDBRD4LMNAALDH1A1
SCHEMBL10294657 0.76 SMN1; SMN2 (0.59) HPGDBRD4LMNAALDH1A1PKM
SCHEMBL9568642 0.76 THRB (0.49) HPGDTHRBLMNAALDH1A1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed