Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568847 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KMT2AHPGDTSHR | |
| SCHEMBL9568708 | 0.85 | MAPK1 (0.37) | ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9730904 | 0.77 | TRPV1 (0.43) | ALDH1A1HSD17B10TRPV1KDM4EKMT2A | |
| SCHEMBL5966689 | 0.76 | TRPV1 (0.59) | ALDH1A1TRPV1KDM4EKMT2AHPGD | |
| SCHEMBL8947317 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TRPV1KDM4EKMT2AHPGD | |
| SCHEMBL8947250 | 0.74 | TRPV1 (0.48) | ALDH1A1TRPV1KDM4EKMT2AHPGD | |
| SCHEMBL8947310 | 0.74 | TRPV1 (0.63) | ALDH1A1TRPV1KDM4EKMT2AHPGD | |
| SCHEMBL8947336 | 0.73 | TRPV1 (0.56) | ALDH1A1TRPV1KDM4EKMT2AHPGD | |
| SCHEMBL8947264 | 0.72 | P2RX7 (0.49) | ALDH1A1HSD17B10TRPV1KDM4EHPGD | |
| SCHEMBL8947140 | 0.71 | HSD11B1 (0.59) | ALDH1A1HSD17B10TRPV1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506011-A1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-30 | — | — | EP | disclosed |