Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350078 | 0.79 | GRIK1 (0.64) | STING1CNR1NPC1LMNARAB9A | |
| SCHEMBL10568558 | 0.77 | GAA (0.45) | CA2CNR1ALDH1A1LMNACCKAR | |
| SCHEMBL6923052 | 0.76 | CA2 (0.54) | CA2CNR1MAPTCCKAR | |
| SCHEMBL9529388 | 0.74 | LMNA (0.63) | CA2ALDH1A1LMNAMAPTFBP1 | |
| SCHEMBL16627058 | 0.73 | NPC1 (0.78) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7983231 | 0.72 | HDAC1 (0.48) | CA2CNR1ALDH1A1IDH1LMNA | |
| SCHEMBL7997094 | 0.72 | CCR2 (0.50) | CA2FBP1CA12CA1CA9 | |
| SCHEMBL2175114 | 0.72 | FBP1 (0.58) | FBP1 | |
| SCHEMBL9486495 | 0.72 | CA12 (0.66) | CA2ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9569774 | 0.72 | ESR1 (0.52) | CA2NPC1RAB9AMAPTFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560554-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5169860-A | Benzofuran or benzothiophene arylsulfonylureas | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |