Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 4/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531321 | 0.84 | BCAT2 (0.52) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| SCHEMBL29389473 | 0.84 | BCAT2 (0.52) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| SCHEMBL707956 | 0.83 | SLC6A3 (0.67) | SLC6A3SLC6A4DRD1DRD2DRD4 | |
| SCHEMBL517 | 0.83 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| SCHEMBL1665535 | 0.83 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| SCHEMBL9373323 | 0.82 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| SCHEMBL6900241 | 0.82 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| Bromomethane SCHEMBL7011845 | 0.81 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| Methylamine SCHEMBL28010440 | 0.81 | BCAT2 (0.53) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| SCHEMBL8875151 | 0.81 | ACHE (0.48) | SLC6A3SLC6A4SLC6A2ACHESCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |