Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.65 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380698 | 0.84 | ALDH1A1 (0.45) | CD274PDCD1ALDH1A1HPGD | |
| SCHEMBL1343377 | 0.82 | DPP4 (0.56) | CD274PDCD1DPP4ALDH1A1HPGD | |
| SCHEMBL22234041 | 0.79 | DPP4 (0.44) | CD274PDCD1DPP4ALDH1A1HPGD | |
| SCHEMBL30462313 | 0.79 | DPP4 (0.44) | CD274PDCD1DPP4ALDH1A1HPGD | |
| SCHEMBL358303 | 0.79 | CD274 (1.00) | CD274PDCD1DPP4ALDH1A1HPGD | |
| SCHEMBL607544 | 0.79 | CD274 (0.71) | CD274PDCD1DPP4EPHX1PTGS1 | |
| SCHEMBL29558512 | 0.79 | CD274 (1.00) | CD274PDCD1DPP4ALDH1A1HPGD | |
| SCHEMBL22910533 | 0.78 | CD274 (0.65) | CD274PDCD1DPP4EPHX1 | |
| SCHEMBL21153739 | 0.77 | CD274 (0.69) | CD274PDCD1DPP4EPHX1PTGS1 | |
| SCHEMBL7107915 | 0.77 | CD274 (0.69) | CD274PDCD1DPP4EPHX1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528148-A1 | Compounds M 871563 A and B, having a azalomycin like structure | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-24 | — | — | EP | disclosed |