SCHEMBL9570639

SCHEMBL9570639

O=CC(c1ccc(Br)cc1)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
CYP2A6 P11509 1/20 0.33
CTSL P07711 3/20 0.31
CTSB P07858 3/20 0.31
CTSS P25774 3/20 0.31
CTSK P43235 3/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ALOX5 P09917 1/20 0.31
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570876 0.81 IDO1 (0.35) CTSLESR1ESR2
SCHEMBL9570745 0.79 CES2 (0.43) CYP1A2
SCHEMBL9570796 0.79 TYR (0.48)
SCHEMBL9570654 0.79 CYP2A6 (0.38) CA1CA2CA5ACA9CYP2A6
SCHEMBL9570777 0.79 TSHR (0.40) CYP2A6
SCHEMBL1225030 0.78 CYP2D6 (0.39) HTR2A
SCHEMBL9570579 0.76 ALDH1A1 (0.42)
SCHEMBL9570684 0.76 TSHR (0.44) CYP1A2
SCHEMBL9570588 0.76 PDE2A (0.32)
SCHEMBL9570882 0.75 PDE2A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed