SCHEMBL9575295

SCHEMBL9575295

CCCCN(c1nc(N(C)C)nc(N(CCCC)C2CC(C)(C)NC(C)(C)C2)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
CREBBP Q92793 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALOX15 P16050 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575399 0.94 DNM1 (0.30)
SCHEMBL1138674 0.94 ALOX15 (0.31) ALOX15
SCHEMBL12100506 0.91
SCHEMBL22202079 0.90
SCHEMBL13360051 0.90 KCNH2 (0.33) ALOX15
SCHEMBL3141109 0.89 CRHR1 (0.34)
SCHEMBL11933246 0.89 CRHR1 (0.36)
SCHEMBL13415295 0.88 ADH1C (0.32)
SCHEMBL3133580 0.88 ADH1C (0.32)
SCHEMBL13449157 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
US-12012542-B2 Flame retardant rotomolded polyolefin BASF SE (DE) 2024-06-18 US disclosed
US-20220282064-A1 STABILIZER COMPOSITION BASF SE (DE) 2022-09-08 US disclosed
US-20220145053-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Phenolic Antioxidants BASF SE (DE) 2022-05-12 US disclosed
US-20210301102-A1 STABILIZED ROTOMOLDED POLYOLEFIN BASF SE (DE) 2021-09-30 US disclosed
US-11118064-B2 Photocurable hardcoat compositions, methods, and articles derived therefrom BASF SE 2021-09-14 US disclosed
US-20210095133-A1 PHOTOCURABLE HARDCOAT COMPOSITIONS, METHODS, AND ARTICLES DERIVED THEREFROM BASF SE (DE) 2021-04-01 US disclosed
US-20210087471-A1 FLAME RETARDANT ROTOMOLDED POLYOLEFIN BASF CORPORATION 2021-03-25 US disclosed
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers BASF SE (DE) 2021-03-09 US disclosed
US-10941286-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered amine light stabilizers BASF SE (DE) 2021-03-09 US disclosed
US-10669403-B2 Polyolefin compositions for building materials BASF SE (DE) 2020-06-02 US disclosed
US-10428204-B2 Polyolefin compositions for building materials BASF SE (DE) 2019-10-01 US disclosed
US-10414900-B2 Pre-exfoliated layered material BYK USA INC. (US) 2019-09-17 US disclosed
US-10227482-B2 Flame retardant polymer compositions BYK USA INC. (US) 2019-03-12 US disclosed
US-20180201838-A1 FLAME-RETARDANT POLYOLEFIN SYSTEMS BASF SE (DE) 2018-07-19 US disclosed
US-20170137613-A1 POLYOLEFIN COMPOSITIONS FOR BUILDING MATERIALS BASF SE (DE) 2017-05-18 US disclosed
US-20090312464-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-12-17 US disclosed
US-7332105-B2 Synergistic UV absorber combination CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-02-19 US disclosed
US-7169835-B2 Stabilizer mixture CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-30 US disclosed
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941286-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered amine light stabilizers PUF60, PARG, PARN LMNA 235/4885CYP1A2 3746/4885THRB 4582/4885
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers PUF60, PCBP1, MORF4L1 LMNA 445/4885CYP1A2 3861/4885THRB 4603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.