Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.57 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 2/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455160 | 0.86 | PGR (0.75) | PGRIL1RNKEAP1ERAP1ALDH1A1 | |
| SCHEMBL9577124 | 0.81 | SMN1; SMN2 (0.56) | PGRPFKFB3MAPTKMT2APKM | |
| SCHEMBL2157528 | 0.80 | PFKFB3 (0.52) | PGRPFKFB3MAPTWDR5KMT2A | |
| SCHEMBL3769126 | 0.79 | PGR (0.73) | PGRMAPTIL1RNKEAP1ERAP1 | |
| SCHEMBL14018756 | 0.79 | ALDH1A1 (0.68) | PGRPFKFB3MAPTWDR5ALDH1A1 | |
| SCHEMBL7577795 | 0.77 | ITGA1 (0.74) | PGRMAPTGPR27ALDH1A1KMT2A | |
| SCHEMBL31696798 | 0.77 | MAPK1 (0.70) | PGRMAPTALDH1A1KMT2AITGA1 | |
| SCHEMBL7627388 | 0.76 | KEAP1 (0.67) | PGRIL1RNKEAP1ERAP1ALDH1A1 | |
| SCHEMBL7508824 | 0.76 | PGR (0.55) | PGRMAPTWDR5IL1RNKEAP1 | |
| SCHEMBL3641667 | 0.75 | MAPT (0.59) | PGRMAPTWDR5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |