Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31701141 | 0.88 | PGR (0.64) | SMN1; SMN2LMNAMAPTHPGDHTT | |
| SCHEMBL10455054 | 0.88 | PGR (0.64) | SMN1; SMN2LMNAMAPTHPGDHTT | |
| SCHEMBL9577186 | 0.81 | PGR (0.57) | LMNAMAPTPGRPFKFB3PKM | |
| SCHEMBL9577140 | 0.77 | NR3C1 (0.44) | SLC22A12PFKFB3PKMMEN1KMT2A | |
| SCHEMBL24876096 | 0.74 | LMNA (0.57) | SMN1; SMN2LMNAMAPTHPGDHTT | |
| SCHEMBL2614387 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMAPTHTTCA1 | |
| SCHEMBL2028750 | 0.72 | PPARG (0.63) | LMNAMAPTPPARGIDH1ALOX12 | |
| SCHEMBL2157528 | 0.72 | PFKFB3 (0.52) | MAPTSLC22A12PGRPFKFB3MEN1 | |
| SCHEMBL9997275 | 0.72 | HSD17B10 (0.73) | HPGDHTTPFKFB3MCL1MEN1 | |
| SCHEMBL14018756 | 0.72 | ALDH1A1 (0.68) | SMN1; SMN2LMNAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |