Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577102 | 0.87 | MCL1 (0.35) | MCL1MEN1KMT2ARXFP1CA1 | |
| SCHEMBL9577188 | 0.87 | MCL1 (0.35) | MCL1MEN1KMT2ARXFP1CA1 | |
| SCHEMBL10455165 | 0.86 | RECQL (0.56) | MCL1MEN1KMT2AEDNRBEDNRA | |
| SCHEMBL9577203 | 0.84 | MCL1 (0.43) | PTGES2MCL1CA1CA2CA9 | |
| SCHEMBL9577237 | 0.84 | KEAP1 (0.50) | MEN1KMT2ARXFP1CA1CA2 | |
| SCHEMBL9577212 | 0.81 | HTT (0.50) | MEN1KMT2ARXFP1CA1CA2 | |
| SCHEMBL9577222 | 0.79 | FABP4 (0.51) | MCL1MEN1KMT2ARXFP1CA1 | |
| SCHEMBL9577096 | 0.76 | EDNRA (0.38) | MEN1KMT2ARXFP1EDNRBEDNRA | |
| SCHEMBL9577227 | 0.75 | LMNA (0.40) | CA1CA2CA9EDNRBEDNRA | |
| SCHEMBL9577127 | 0.74 | RECQL (0.58) | MCL1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4959500-A | Polybrominated bis sulfonamides | ETHYL CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |