Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 2/20 | 0.34 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577188 | 1.00 | MCL1 (0.35) | MCL1TSHRHPGDHTTMEN1 | |
| SCHEMBL9577208 | 0.87 | PTGES2 (0.41) | MCL1MEN1KMT2ARXFP1CA1 | |
| SCHEMBL9577212 | 0.82 | HTT (0.50) | HTTMEN1KMT2ARXFP1CA1 | |
| SCHEMBL9577237 | 0.78 | KEAP1 (0.50) | HTTMEN1KMT2ARXFP1CA1 | |
| SCHEMBL9577096 | 0.78 | EDNRA (0.38) | HTTMEN1KMT2ARXFP1EDNRB | |
| SCHEMBL10455165 | 0.77 | RECQL (0.56) | MCL1HPGDHTTMEN1KMT2A | |
| SCHEMBL9577222 | 0.77 | FABP4 (0.51) | MCL1HTTMEN1KMT2ARXFP1 | |
| SCHEMBL9577227 | 0.76 | LMNA (0.40) | TSHRHTTCA1CA2EDNRB | |
| SCHEMBL157499 | 0.72 | CA2 (0.36) | CA1CA2EDNRBEDNRA | |
| SCHEMBL30388332 | 0.72 | CA2 (0.36) | CA1CA2EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4981890-A | POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE | ETHYL CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4957958-A | IMPROVED MELT FLOW | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |